AS WOMEN OVER 40 YEARS AND PCOS PATIENTS SUFFER FROM LOW INCIDENCE OF PREGNANCY AFTER ICSI PROCEDURE DUE TO HIGH INCIDENCE OF PRODUCTION OF IMMATURE OOCYTES GV OR INCOMPLETE MATURE OOCYTES METAPHASE1-A NEW MIXTURE FROM DEPROTEINSED EXTRACT BY CALVES BLOOD WITH ACTIVATED RETUCULO ENDOTHELIAL SYSTEM,WERE MIXED IN TWO TYPES OF CONCENTRATION WITH THE WELL KNOWN ISMI ,CULTURE MEDIA WERE ABLE TO MAINTAIN THE OOCYTES TO FULL MATURATION IN VITRO AND CONSEQUENTLY BE READY FOR SPERM INJECTION AND FERTILIZATION.ALSO THE TWO MIXTURE BEI & BE2 WERE ABLE TO INCREASE MOTILITY OF SPERM IN IUI PROCEDURES AND CONSEQUENTLY INCREASE THE SUCCESS OF RATE
